Background:

Participates in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of some MITRAC complex, a cytochrome c oxidase (COX) assembly intermediate complex. TIM21 probably shuttles between the presequence translocase and respiratory-chain assembly intermediates in a process that promotes incorporation of early nuclear-encoded subunits into these complexes.

Applications:

ELISA, WB, IHC

Name of antibody:

TIMM21

Immunogen:

Fusion protein of human TIMM21

Full name:

translocase of inner mitochondrial membrane 21

Synonyms:

TIM21; HSPC154; C18orf55

SwissProt:

Q9BVV7

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human lung cancer;

IHC Recommend dilution:

20-100

WB Predicted band size:

28 kDa

WB Positive control:

SKOV3 cell lysate

WB Recommended dilution:

200-1000