Background:

This gene encodes a multi-pass membrane protein that is localized to the endoplasmic reticulum. It belongs to the sulfatase family and hydrolyzes several 3-beta-hydroxysteroid sulfates, which serve as metabolic precursors for estrogens, androgens, and cholesterol. Mutations in this gene are associated with X-linked ichthyosis (XLI). Alternatively spliced transcript variants resulting from the use of different promoters have been described for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

STS

Immunogen:

Synthetic peptide of human STS

Full name:

steroid sulfatase (microsomal), isozyme S

Synonyms:

ES; ASC; XLI; ARSC; SSDD; ARSC1

SwissProt:

P08842

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

10-50

WB Predicted band size:

65 kDa

WB Positive control:

Hela cell lysate

WB Recommended dilution:

200-1000