Background:

This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome); translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome.

Applications:

WB

Name of antibody:

SRY

Immunogen:

Synthesized peptide derived from internal of human SRY.

Full name:

sex determining region Y

Synonyms：

TDF; TDY; SRXX1; SRXY1

SwissProt:

Q05066

WB Predicted band size:

24 kDa

WB Positive control:

Hela cells lysate

WB Recommended dilution:

500-3000