Background:

This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, WB

Name of antibody:

SPI1

Immunogen:

Synthetic peptide of human SPI1

Full name:

Spi-1 proto-oncogene

Synonyms:

OF; PU.1; SFPI1; SPI-1; SPI-A

SwissProt:

P17947

ELISA Recommended dilution:

5000-10000

WB Predicted band size:

31 kDa

WB Positive control:

Mouse liver tissue lysate

WB Recommended dilution:

500-2000