中文名稱:兔抗SNCA(Ab-125) 多克隆抗體
英文名稱: Anti-SNCA(Ab-125) rabbit polyclonal antibody
別 名: PD1; NACP; PARK1; PARK4
相關(guān)類(lèi)別: 一抗
儲(chǔ) 存: 冷凍(-20℃) 避光
宿 主: Rabbit
抗 原: SNCA(Ab-125)
反應(yīng)種屬: Human Mouse Rat
標(biāo) 記 物: Unconjugate
克隆類(lèi)型: Unconjugate
技術(shù)規(guī)格
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Background: |
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. |
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Applications: |
WB |
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Name of antibody: |
SNCA(Ab-125) |
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Immunogen: |
Synthesized non-phosphopeptide derived from human Synuclein-α around the phosphorylation site of tyrosine 125 (E-A-Y(p)-E-M). |
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Full name: |
synuclein, alpha (non A4 component of amyloid precursor) |
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Synonyms: |
PD1; NACP; PARK1; PARK4 |
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SwissProt: |
P37840 |
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WB Predicted band size: |
14 kDa |
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WB Positive control: |
Rat brain and mouse brain tissue lysates |
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WB Recommended dilution: |
500-3000 |