Background:

This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function. Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis.

Applications:

ELISA, WB, IHC

Name of antibody:

S1PR3

Immunogen:

Synthetic peptide of human S1PR3

Full name:

Sphingosine-1-phosphate receptor 3

Synonyms：

EDG3; LPB3; S1P3; EDG-3

SwissProt:

Q99500

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human cervical cancer and Human thyroid cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

42 kDa

WB Positive control:

Human fetal brain tissue

WB Recommended dilution:

1000-5000